Full publication list on Google Scholar

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Preprints
 

Schwob, M., Hooten, M., Narasimhan, V.M., Composite dyadic models for spatio-temporal data, arXiv, 2311.01341, 2023. (Paper) 

Pandey, D., Harris., M. H., Garud, N., Narasimhan, V. M., Understanding natural selection in Holocene Europe using multi-locus genotype identity scans, bioRxiv, 2022.11.30.518528. DOI: 10.1101/2023.04.24.538113

Le, M., Smith, O., Akbari, A., Harpak, A., Reich, D., Narasimhan, V. M., 1,000 ancient genomes uncover 10,000 years of natural selection in Europe. bioRxiv, 2022.08.24.505188 (Paper, doi: 10.1101/2022.08.24.505188)

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Published

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Zhou, A., Mihelic, S., Engelman, S., Tomar, A., Dunn, A. K., Narasimhan, V. M., A deep learning approach for improving two-photon vascular imaging speeds, Bioengineering 2024, 11(2), 111,  (Paper, doi: 10.1101/2022.11.30.518528) 

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Flynn, B.I., Javan, E.M., Lin, E., Trutner, Z., Koenig, K., Anighoro, K. O., Kun, E., Gupta, A., Singh, T., Jayakumar, P., Narasimhan, V.M., Deep learning based phenotyping of medical images improves power for gene discovery of complex disease, Nature Digital Medicine, 2023.03.06.5300086. DOI: 10.1101/2023.03.07.23286909

Kun, E., Javan, E. M., Smith, O., Gulamali, F., de la Fuente, J., Flynn, B., Vajrala, K., Trutner, Z., Jayakumar, P., Tucker-Drob, E. M., Sohail, M., Singh, T., Narasimhan, V. M., The genetic architecture and evolution of the human skeletal form. Science, 2023.01.03.521284 (Paper, doi: 10.1101/2023.01.03.521284) - cover article in Science Magazine

Kun, E., Narasimhan, V. M., Fast-evolving genomic regions underlie human brain development. Nature, 614, 37-38 (Paper, doi: 10.1038/d41586-023-00069-2)

Scott, C., Cárdenas, A., Mah M., Narasimhan, V. M., Rohland, N., Toth, L., Voolstra, C., Reich, D., Matz, M, Millennia-old coral holobiont DNA provides insight into future adaptive trajectories, Molecular Ecology. 2022; 31:4979-4990; (Paper, Supplementary Materials, doi: 10.1111/mec.16642)

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Yan, J., Patterson, N., Narasimhan, V. M., miqoGraph: Fitting admixture graphs using mixed-integer quadratic optimization. Bioinformatics. btaa988; (Paper, Supplementary Materials, doi: 10.1093/bioinformatics/btaa988)

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Cuvertino, S., Hartill, V., (12 other authors), Narasimhan, V. M.*, et al. A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome. Genetics in Medicine. 22:867-877; (Paper, Supplementary Materials, doi: 10.1038/s41436-019-0743-3)

Narasimhan, V. M.*, Patterson, N. J.*, et al. The Formation of Human Populations in South and Central Asia; Science. 365:eaat7487; (Paper, Supplementary Materials, Genotype data, Online Data Visualizer, doi: 10.1126/science.aat7487)  - the most widely accessed genetics/genomics paper in the history of the bioRxiv pre-print server.

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Narasimhan, V. M.*, Rohland, N., et.al. An Ancient Harappan Genome Lacks Ancestry from Steppe Pastoralists or Iranian Farmers. Cell. 179:1–7; (Paper, Genotype data, Online Data Visualizer, doi: 10.1016/j.cell.2019.08.048)

Hajdinjak, M., Fu, Q., Hübner, A., (4 other authors), Narasimhan, V. M., et al. Reconstructing the genetic history of late Neanderthals. Nature. 555, 652–656; (Paper, Supplementary Materials, doi: 10.1038/nature26151)

Xue, Y., Mezzavilla, M., Haber, M., McCarthy, S., Chen, Y., Narasimhan, V. M., et al. Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations. Nature Communications. 8, 15927; (Paper, Supplementary Materials, doi: 10.1038/ncomms15927)

Narasimhan, V. M., Rahbari, R., Scally, A., Wuster, A., Mason, D., Xue, Y., Wright, J., Trembath, R. C., Maher, E. R., van Heel, D. A., Auton, A., Hurles, M. E., Tyler-Smith, C. & Durbin, R. Estimating the human mutation rate from autozygous segments reveals population differences in human mutational processes. Nature Communications. 8, 303; (Paper, Supplementary Materials, doi: 10.1038/s41467-017-00323-y)

Narasimhan, V. M., Danecek, P., Scally, A., Xue, Y., Tyler-Smith, C. & Durbin, R. BCFtools/RoH: a hidden Markov model approach for detecting autozygosity from next-generation sequencing data. Bioinformatics. 32, 1749–51. (Paper, Supplementary Materials, doi: 10.1093/bioinformatics/btw044) 

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Chappell, J., Harman, J. L., Narasimhan, V. M., et al. Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis Models. Circulation Research. 119, 1313–1323 (2016). (Paper, Supplementary Materials, doi: 10.1161/CIRCRESAHA.116.309799)

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Narasimhan, V. M., Hunt, K. A., Mason, D., et al. Health and population effects of rare gene knockouts in adult humans with related parents. Science. 352:474-77; (Paper, Supplementary Materials, doi: 10.1126/science.aac8624)

Narasimhan, V. M., Xue, Y. & Tyler-Smith, C. Human Knockout Carriers: Dead, Diseased, Healthy, or Improved? Trends in Molecular Medicine. 22, 341-51. (Paper, doi: 10.1016/j.molmed.2016.02.006)

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Xue Y*, Prado-Martinez J*, Sudmant PH*, Narasimhan, V. M.*, et al. Mountain gorilla genomes reveal the impact of long-term population decline and inbreeding. Science. 348 (6231) :242-5. (Paper, Supplementary Materials, doi: 10.1126/science.aaa3952)

Pelle, K. G., Oh, K., Buchholz, K., Narasimhan, V. M., Joice, R., Milner, D. A., Brancucci, N., Ma, S., Voss, T. S., Ketman, K., Seydel, K. B., Taylor, T. E., Barteneva, N. S., Huttenhower, C. & Marti, M. Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection. Genome Medicine. 7, 19. (Paper, Supplementary Materials, doi: 10.1186/s13073-015-0133-7)

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Joice, R.*, Narasimhan, V. M.*, Montgomery, J., Sidhu, A. B., Oh, K., Meyer, E., Pierre-Louis, W., Seydel, K., Milner, D., Williamson, K., Wiegand, R., Ndiaye, D., Daily, J., Wirth, D., Taylor, T., Huttenhower, C. & Marti, M. Inferring Developmental Stage Composition from Gene Expression in Human Malaria. PLoS Computational Biology. 9, e1003392. (Paper, Supplementary Materials, doi: 10.1371/journal.pcbi.1003392)

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Segata, N., Waldron, L., Ballarini, A., Narasimhan, V. M., Jousson, O. & Huttenhower, C. Metagenomic microbial community profiling using unique clade-specific marker genes. Nature Methods. 9, 1–7. (Paper, Supplemetary Materials, doi: 10.1038/nmeth.2066)