Publications

Full publication list on Google Scholar

Yan, J., Patterson, N., Narasimhan, V. M., miqoGraph: Fitting admixture graphs using mixed-integer quadratic optimization. Bioinformatics. btaa988; (Paper, Supplementary Materials, doi: 10.1093/bioinformatics/btaa988)

 

Cuvertino, S., Hartill, V., (12 other authors), Narasimhan, V. M.*, et al. A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome. Genetics in Medicine. 22:867-877; (Paper, Supplementary Materialsdoi: 10.1038/s41436-019-0743-3)
 

Narasimhan, V. M.*, Patterson, N. J.*, et al. The Formation of Human Populations in South and Central Asia; Science. 365:eaat7487; (PaperSupplementary MaterialsGenotype dataOnline Data Visualizer, doi: 10.1126/science.aat7487)  - the most widely accessed genetics/genomics paper in the history of the bioRxiv pre-print server.

Narasimhan, V. M.*, Rohland, N., et.al. An Ancient Harappan Genome Lacks Ancestry from Steppe Pastoralists or Iranian Farmers. Cell. 179:1–7; (PaperGenotype dataOnline Data Visualizer, doi: 10.1016/j.cell.2019.08.048)

Hajdinjak, M., Fu, Q., Hübner, A., (4 other authors), Narasimhan, V. M., et al. Reconstructing the genetic history of late Neanderthals. Nature. 555, 652–656; (PaperSupplementary Materialsdoi: 10.1038/nature26151)


Xue, Y., Mezzavilla, M., Haber, M., McCarthy, S., Chen, Y., Narasimhan, V. M., et al. Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations. Nature Communications. 8, 15927; (Paper, Supplementary Materials, doi: 10.1038/ncomms15927)

Narasimhan, V. M., Rahbari, R., Scally, A., Wuster, A., Mason, D., Xue, Y., Wright, J., Trembath, R. C., Maher, E. R., van Heel, D. A., Auton, A., Hurles, M. E., Tyler-Smith, C. & Durbin, R. Estimating the human mutation rate from autozygous segments reveals population differences in human mutational processes. Nature Communications. 8, 303; (Paper, Supplementary Materials, doi: 10.1038/s41467-017-00323-y)


Narasimhan, V. M., Danecek, P., Scally, A., Xue, Y., Tyler-Smith, C. & Durbin, R. BCFtools/RoH: a hidden Markov model approach for detecting autozygosity from next-generation sequencing data. Bioinformatics. 32, 1749–51. (Paper, Supplementary Materials, doi: 10.1093/bioinformatics/btw044) 

Chappell, J., Harman, J. L., Narasimhan, V. M., et al. Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis Models. Circulation Research. 119, 1313–1323 (2016). (Paper, Supplementary Materials, doi: 10.1161/CIRCRESAHA.116.309799)

Narasimhan, V. M., Hunt, K. A., Mason, D., et al. Health and population effects of rare gene knockouts in adult humans with related parents. Science. 352:474-77; (PaperSupplementary Materials, doi: 10.1126/science.aac8624)

Narasimhan, V. M., Xue, Y. & Tyler-Smith, C. Human Knockout Carriers: Dead, Diseased, Healthy, or Improved? Trends in Molecular Medicine. 22, 341-51. (Paper, doi: 10.1016/j.molmed.2016.02.006)

Xue Y*, Prado-Martinez J*, Sudmant PH*, Narasimhan, V. M.*, et al. Mountain gorilla genomes reveal the impact of long-term population decline and inbreedingScience. 348 (6231) :242-5. (PaperSupplementary Materials, doi: 10.1126/science.aaa3952)

Pelle, K. G., Oh, K., Buchholz, K., Narasimhan, V. M., Joice, R., Milner, D. A., Brancucci, N., Ma, S., Voss, T. S., Ketman, K., Seydel, K. B., Taylor, T. E., Barteneva, N. S., Huttenhower, C. & Marti, M. Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection. Genome Medicine. 7, 19. (Paper, Supplementary Materials, doi: 10.1186/s13073-015-0133-7)

Joice, R.*, Narasimhan, V. M.*, Montgomery, J., Sidhu, A. B., Oh, K., Meyer, E., Pierre-Louis, W., Seydel, K., Milner, D., Williamson, K., Wiegand, R., Ndiaye, D., Daily, J., Wirth, D., Taylor, T., Huttenhower, C. & Marti, M. Inferring Developmental Stage Composition from Gene Expression in Human Malaria. PLoS Computational Biology. 9, e1003392. (Paper, Supplementary Materials, doi: 10.1371/journal.pcbi.1003392)

Segata, N., Waldron, L., Ballarini, A., Narasimhan, V. M., Jousson, O. & Huttenhower, C. Metagenomic microbial community profiling using unique clade-specific marker genes. Nature Methods. 9, 1–7. (Paper, Supplemetary Materials, doi: 10.1038/nmeth.2066)

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